Meir was selected by NASA in 2013. Before becoming an astronaut, her career as a scientist focused on the physiology of animals in extreme environments. She previously served as flight engineer on the International Space Station for Expeditions 61 and 62 and participated in the first all-female spacewalks.
A portrait of Meir taken on Sept. 23, 2025, was chosen as a 2025 NASA Photographer of the Year finalist. The specific experiments or activities Meir will conduct on the Crew-12 mission have not been disclosed, and the exact launch date and mission duration remain unannounced.