According to Daily Express - Health, Dr Punam Krisham, an NHS GP and health expert, said that certain fruit juices can block the transporter in the gut that absorbs fexofenadine, reducing its effectiveness. The warning comes as the Met Office forecasts a 'very high' pollen count on Saturday, April 25, across western regions including Wales, north-east England and Northern Ireland. On Sunday, April 26, pollen levels will remain 'high' for most of the country.
Close to 10 million people in England are affected by hay fever, according to the Met Office, and the number is rising annually. Hay fever cannot be cured, but symptoms can be alleviated with measures or medications. Common treatments include non-drowsy antihistamine tablets such as cetirizine, loratadine, and fexofenadine. The exact mechanism by which fruit juices block the transporter and whether other antihistamines are affected remain unclear.
I think this is lesser known. There's a very common antihistamine called fexofenadine, which people take now. What people don't know is that there is a transporter in the gut that fexofenadine is absorbed via. Now, there are certain fruit juices like orange juice, grapefruit juice and apple juice that can actually block that transporter, so it means that